Adenine
C₅H₅N₅·135.127 g/mol·Biochemical·CID 190
NucleobaseEssential
A purine nucleobase that pairs with thymine (in DNA) or uracil (in RNA) via two hydrogen bonds. Also a component of ATP, NAD, and FAD — fundamental cofactors in metabolism.
IUPAC: 7H-purin-6-amine
Also known as: 73-24-5, 6-Aminopurine, 1H-Purin-6-amine, 7H-Purin-6-amine, Adeninimine (+14 more)
Molecular Structure
Molecular Propertiesmass · H-bonds · stereo
Molecular Weight
135.130g/mol
Exact Mass
135.054495Da
Monoisotopic Mass
135.054495Da
XLogP
-0.1
Polar Surface Area
80.5Ų
Complexity
127
Formal Charge
0
H-Bond Donors
2
H-Bond Acceptors
4
Rotatable Bonds
0
Heavy Atoms
10
Stereo Centers
0
Bond Stereo
0
Drug-Likeness (Lipinski's Rule of Five)
✓ 135.1 g/mol
MW ≤ 500
✓ -0.1
LogP ≤ 5
✓ 2
H-bond donors ≤ 5
✓ 4
H-bond acceptors ≤ 10
Passes all rules — good oral bioavailability predicted
GHS Hazard Classification
Danger
Hazards
H301Toxic if swallowed
Source: PubChem GHS Classification. Always consult the SDS for handling.
Chemical IdentifiersSMILES · InChI
InChI
InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)
Constituent Elements
Isomers8 compounds with formula C₅H₅N₅
7H-purin-2-amine
CID 9955 · 135.1 g/mol
1H-pyrazolo[3,4-d]pyrimidin-4-amine
CID 75420 · 135.1 g/mol
2-hydrazinylpyrimidine-5-carbonitrile
CID 1478409 · 135.1 g/mol
2,4-diaminopyrimidine-5-carbonitrile
CID 282115 · 135.1 g/mol
[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CID 3161243 · 135.1 g/mol
1H-imidazo[4,5-d]pyridazin-4-amine
CID 5469585 · 135.1 g/mol
tetrazolo[1,5-a]pyridin-6-amine
CID 346456 · 135.1 g/mol
N'-[(Z)-2-amino-1,2-dicyanoethenyl]methanimidamide
CID 5468431 · 135.1 g/mol