Sodium Fluoride
NaF·41.988 g/mol·Salts & Minerals·CID 5235
DentalCommon
An ionic compound used to fluorinate drinking water (typically 0.7 ppm) and in toothpaste to prevent dental cavities. Fluoride incorporates into tooth enamel as fluorapatite, which resists acid dissolution better than hydroxyapatite.
IUPAC: sodium fluoride
Also known as: 7681-49-4, Sodium fluoride (NaF), Fluoride, sodium, Florocid, Pergantene (+14 more)
Molecular Structure
Molecular Propertiesmass · H-bonds · stereo
Molecular Weight
41.988g/mol
Exact Mass
41.988172Da
Monoisotopic Mass
41.988172Da
XLogP
—
Polar Surface Area
0.0Ų
Complexity
2
Formal Charge
0
H-Bond Donors
0
H-Bond Acceptors
1
Rotatable Bonds
0
Heavy Atoms
2
Stereo Centers
0
Bond Stereo
0
Drug-Likeness (Lipinski's Rule of Five)
✓ 42.0 g/mol
MW ≤ 500
? —
LogP ≤ 5
✓ 0
H-bond donors ≤ 5
✓ 1
H-bond acceptors ≤ 10
Passes all rules — good oral bioavailability predicted
GHS Hazard Classification
Danger
Hazards
H301Toxic if swallowedH315Causes skin irritationH319Causes serious eye irritationH318Causes serious eye damageH370Causes damage to organsH372Causes damage to organs through prolonged or repeated exposureH373May causes damage to organs through prolonged or repeated exposureH402Harmful to aquatic lifeH314Causes severe skin burns and eye damageH341Suspected of causing genetic defects
Source: PubChem GHS Classification. Always consult the SDS for handling.