Chloroform
CHCl₃·119.378 g/mol·Organic·CID 6212
SolventHistorical
Trichloromethane — a dense, sweet-smelling liquid historically used as an anesthetic (1847). Now used primarily as a solvent and precursor to PTFE (Teflon). A suspected carcinogen; exposure regulated in drinking water.
IUPAC: chloroform
Also known as: Trichloromethane, 67-66-3, Trichlormethan, Trichloroform, Formyl trichloride (+14 more)
Molecular Structure
Molecular Propertiesmass · H-bonds · stereo
Molecular Weight
119.370g/mol
Exact Mass
117.914383Da
Monoisotopic Mass
117.914383Da
XLogP
2.3
Polar Surface Area
0.0Ų
Complexity
8
Formal Charge
0
H-Bond Donors
0
H-Bond Acceptors
0
Rotatable Bonds
0
Heavy Atoms
4
Stereo Centers
0
Bond Stereo
0
Drug-Likeness (Lipinski's Rule of Five)
✓ 119.4 g/mol
MW ≤ 500
✓ 2.3
LogP ≤ 5
✓ 0
H-bond donors ≤ 5
✓ 0
H-bond acceptors ≤ 10
Passes all rules — good oral bioavailability predicted
GHS Hazard Classification
Danger
Hazards
H302Harmful if swallowedH315Causes skin irritationH319Causes serious eye irritationH331Toxic if inhaledH351Suspected of causing cancerH372Causes damage to organs through prolonged or repeated exposureH336May cause drowsiness or dizzinessH361Suspected of damaging fertility or the unborn childH373May causes damage to organs through prolonged or repeated exposureH318Causes serious eye damage
Source: PubChem GHS Classification. Always consult the SDS for handling.
Constituent Elements
Isomers8 compounds with formula CHCl₃
trichloro(deuterio)methane
CID 71583 · 120.4 g/mol
trichloro(113C)methane
CID 10176135 · 120.4 g/mol
trichloro(deuterio)(113C)methane
CID 101644856 · 121.4 g/mol
trichloro(114C)methane
CID 12224983 · 121.4 g/mol
trichloro(tritio)methane
CID 53872522 · 121.4 g/mol
CID 59268277
CID 59268277 · 119.4 g/mol
chloro(chloromethylidene)-lambda3-chlorane
CID 77520523 · 119.4 g/mol
1lambda3-chlora-2,4-dichloroniabicyclo[1.1.0]butane
CID 139120468 · 119.4 g/mol