Uracil
C₄H₄N₂O₂·112.087 g/mol·Biochemical·CID 1174
Nucleobase
A pyrimidine nucleobase found in RNA but not DNA, where thymine takes its place. Pairs with adenine via two hydrogen bonds. The methyl group that distinguishes thymine from uracil helps DNA repair enzymes detect deaminated cytosine.
IUPAC: 1H-pyrimidine-2,4-dione
Also known as: 66-22-8, pyrimidine-2,4(1H,3H)-dione, 2,4(1H,3H)-Pyrimidinedione, Pyrod, Hybar X (+14 more)
Molecular Structure
Molecular Propertiesmass · H-bonds · stereo
Molecular Weight
112.090g/mol
Exact Mass
112.027277Da
Monoisotopic Mass
112.027277Da
XLogP
-1.1
Polar Surface Area
58.2Ų
Complexity
161
Formal Charge
0
H-Bond Donors
2
H-Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
8
Stereo Centers
0
Bond Stereo
0
Drug-Likeness (Lipinski's Rule of Five)
✓ 112.1 g/mol
MW ≤ 500
✓ -1.1
LogP ≤ 5
✓ 2
H-bond donors ≤ 5
✓ 2
H-bond acceptors ≤ 10
Passes all rules — good oral bioavailability predicted
GHS Hazard Classification
Warning
Hazards
H315Causes skin irritationH319Causes serious eye irritationH335May cause respiratory irritation
Source: PubChem GHS Classification. Always consult the SDS for handling.
Constituent Elements
Isomers8 compounds with formula C₄H₄N₂O₂
1,2-dihydropyridazine-3,6-dione
CID 21954 · 112.1 g/mol
but-2-ynediamide
CID 10971 · 112.1 g/mol
1H-pyrazole-5-carboxylic acid
CID 574310 · 112.1 g/mol
1H-imidazole-5-carboxylic acid
CID 14080 · 112.1 g/mol
4-hydroxy-1H-pyrimidin-6-one
CID 14512 · 112.1 g/mol
4-oxido-1H-pyrazin-4-ium-2-one
CID 274093 · 112.1 g/mol
2-nitro-1H-pyrrole
CID 96706 · 112.1 g/mol
1H-pyrazole-4-carboxylic acid
CID 3015937 · 112.1 g/mol