Urea
CH₄N₂O·60.056 g/mol·Organic·CID 1176
FertilizerHistorical
The main nitrogen waste product of mammalian metabolism, excreted in urine. The first organic compound synthesized from inorganic precursors (Wöhler, 1828), disproving vitalism. Today ~180 million tonnes produced annually for fertilizer.
IUPAC: urea
Also known as: 57-13-6, carbamide, Carbonyldiamide, Ureophil, Carbonyldiamine (+14 more)
Molecular Structure
Molecular Propertiesmass · H-bonds · stereo
Molecular Weight
60.056g/mol
Exact Mass
60.032363Da
Monoisotopic Mass
60.032363Da
XLogP
-1.4
Polar Surface Area
69.1Ų
Complexity
29
Formal Charge
0
H-Bond Donors
2
H-Bond Acceptors
1
Rotatable Bonds
0
Heavy Atoms
4
Stereo Centers
0
Bond Stereo
0
Drug-Likeness (Lipinski's Rule of Five)
✓ 60.1 g/mol
MW ≤ 500
✓ -1.4
LogP ≤ 5
✓ 2
H-bond donors ≤ 5
✓ 1
H-bond acceptors ≤ 10
Passes all rules — good oral bioavailability predicted
Constituent Elements
Isomers8 compounds with formula CH₄N₂O
diamino(114C)methanone
CID 11457650 · 62.0 g/mol
diamino(113C)methanone
CID 636363 · 61.0 g/mol
formohydrazide
CID 12229 · 60.1 g/mol
N'-hydroxymethanimidamide
CID 9561073 · 60.1 g/mol
1,1,3,3-tetradeuteriourea
CID 2723980 · 64.1 g/mol
bis(15N)(azanyl)methanone
CID 10197611 · 62.0 g/mol
N-methylnitrous amide
CID 108081 · 60.1 g/mol
N'-hydroxymethanimidamide
CID 12227 · 60.1 g/mol