Glutamic Acid
C₅H₉NO₄·147.130 g/mol·Amino Acids·CID 33032
Amino AcidNeurotransmitter
The most abundant excitatory neurotransmitter in the brain. Its sodium salt (MSG, monosodium glutamate) produces the umami taste. Negatively charged at physiological pH. Central to nitrogen metabolism as the hub of transamination reactions.
IUPAC: (2S)-2-aminopentanedioic acid
Also known as: GLUTAMIC ACID, 56-86-0, (2S)-2-Aminopentanedioic acid, L-glutamate, (S)-2-Aminopentanedioic acid (+14 more)
Molecular Structure
Molecular Propertiesmass · H-bonds · stereo
Molecular Weight
147.130g/mol
Exact Mass
147.053158Da
Monoisotopic Mass
147.053158Da
XLogP
-3.7
Polar Surface Area
101.0Ų
Complexity
145
Formal Charge
0
H-Bond Donors
3
H-Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
10
Stereo Centers
1
Bond Stereo
0
Drug-Likeness (Lipinski's Rule of Five)
✓ 147.1 g/mol
MW ≤ 500
✓ -3.7
LogP ≤ 5
✓ 3
H-bond donors ≤ 5
✓ 5
H-bond acceptors ≤ 10
Passes all rules — good oral bioavailability predicted
GHS Hazard Classification
Danger
Hazards
H314Causes severe skin burns and eye damageH318Causes serious eye damage
Source: PubChem GHS Classification. Always consult the SDS for handling.
Chemical IdentifiersSMILES · InChI
InChI
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
Constituent Elements
Isomers8 compounds with formula C₅H₉NO₄
(2R)-2-(methylamino)butanedioic acid
CID 22880 · 147.1 g/mol
(2R)-2-aminopentanedioic acid
CID 23327 · 147.1 g/mol
2-aminopentanedioic acid
CID 611 · 147.1 g/mol
(2S)-2-acetamido-3-hydroxypropanoic acid
CID 65249 · 147.1 g/mol
(2S)-3-acetyloxy-2-aminopropanoic acid
CID 99478 · 147.1 g/mol
2-[hydroxy(propan-2-yl)amino]-2-oxoacetic acid
CID 73284 · 147.1 g/mol
2-(methylamino)butanedioic acid
CID 4376 · 147.1 g/mol
(2S)-2-azaniumyl-5-hydroxy-5-oxopentanoate
CID 44272391 · 147.1 g/mol